What is the duration of Vyvanse in your body?

What is the duration of Vyvanse in your body?

Understanding Vyvanse: Half-Life, Uses, and Effectiveness

Key Points

  • Vyvanse is a medication used to treat ADHD in adults and children and binge eating disorder in adults.
  • The active compound in Vyvanse, dextroamphetamine, has a half-life of 12 hours and is eliminated from the body in about 2.5 days.
  • Vyvanse is a long-acting medication and is taken once a day in the morning.
  • It can take up to 12 weeks for patients with binge eating disorder to show a significant reduction in their number of binge days per week.
  • Vyvanse is a controlled substance and can be abused or lead to drug dependence.
  • About Vyvanse

    Vyvanse (generic name: lisdexamfetamine dimesylate) is a medication used for the treatment of attention-deficit hyperactivity disorder (ADHD) in adults and children ages 6 to 17 years of age, as well as moderate-to-severe binge eating disorder (BED) in adults. The ingredient in Vyvanse, lisdexamfetamine dimesylate, is considered a prodrug. Prodrugs are inactive when first taken. Once they are in your system, they are converted to an active medication. Lisdexamfetamine dimesylate is broken down to dextroamphetamine (the active agent) and l-lysine, an amino acid in your body.

    Vyvanse Half-Life and Elimination

    Dextroamphetamine, the active chemical for Vyvanse, has a half-life of roughly 12 hours. It takes about five half-lives for a drug to be eliminated from your body, so after 60 hours, or 2.5 days, most of the drug is eliminated. However, the half-life and elimination of a drug can vary from person-to-person based on age, weight, genetics, other medicines they take or even other medical conditions.

    How Long is Vyvanse Effective?

    Vyvanse (lisdexamfetamine dimesylate) is taken only once a day, in the morning, and is used to treat either attention deficit hyperactivity disorder (ADHD) or binge eating disorder (BED). Because it is a long-acting medication, it can be taken only once a day.


    In clinical studies in children 6 to 12 years of age with ADHD, the effects of Vyvanse started at 1.5 hours after a dose and were sustained throughout the day. From questionnaires given to parents, it was found that behavioral effects in their children were evident in the morning (approximately 10 am), afternoon (approximately 2 pm), and early evening (approximately 6 pm).

    In adults with ADHD, Vyvanse improves attention at 2 hours and 14 hours after taking a dose.


    In clinical research with Vyvanse, a “binge day” was defined as a day in which the patient had at least one binge episode. In the treatment of binge eating disorder (BED), it can take up to 12 weeks for patients to show a significant reduction in their number of binge days per week.

    In longer studies, Vyvanse effectively controlled binge-eating disorder symptoms for at least 38 weeks.

    How to Use Vyvanse

    Always be sure to take Vyvanse exactly as prescribed by your doctor. Vyvanse is taken in the morning as a once-daily oral medication. Avoid afternoon or evening doses because it can interfere with your sleep. Vyvanse can be taken with or without food. Vyvanse is often started at a lower dose and increased based on your response.

    Vyvanse comes in oral capsules or chewable tablets. If needed, the capsules can be opened and mixed with yogurt, water or orange juice; ask your pharmacist how to do this.

    Your doctor may want to stop your Vyvanse treatment for a period of time to check your symptoms and your condition. Also, if you have kidney disease, your doctor may need to lower your dose.

    Vyvanse Side Effects and Precautions

    Vyvanse is a controlled substance in the class of drugs known as central nervous system (CNS) stimulants. It can be abused or lead to drug dependence. Your doctor will assess the risk for abuse prior to prescribing Vyvanse and monitor you for abuse and dependence.

    Keep Vyvanse in a safe place to prevent misuse, abuse or theft by others.

    Do not take Vyvanse if:

    • You or your child are
    • admin


      Leave a Reply

      Your email address will not be published. Required fields are marked *