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What is Lorazepam and how does it work?

Lorazepam is a benzodiazepine medication that acts on the brain and nerves to produce a calming effect. It works by increasing the levels of a natural chemical called GABA in the body. This medication can also be used for short-term treatment of insomnia, which is a condition characterized by poor sleep quality or quantity.

What are the dosages of Lorazepam?

Lorazepam is taken orally and the dose, frequency, and duration of therapy should be personalized based on the patient’s condition and response to the medication. For anxiety, most patients typically start with a daily dose of 2 to 3 mg, divided into 2-3 administrations. For insomnia related to anxiety or transient stress, a single dose of 2-4 mg is usually taken at bedtime. Elderly patients may start with an initial dose of 1 to 2 mg per day, adjusted as needed or tolerated. The dosage should be increased gradually to minimize adverse effects.

What are the side effects associated with Lorazepam?

Common side effects of Lorazepam include sedation, dizziness, unsteadiness, weakness, fatigue, drowsiness, amnesia, confusion, disorientation, depression, suicidal thoughts, vertigo, sleep apnea, muscle spasms, restlessness, jerky movements, ataxia, respiratory depression, tremor, convulsions/seizures, visual disturbances, difficulty speaking, low blood pressure, changes in libido or impotence, jaundice, hypersensitivity reactions, nausea, constipation, changes in appetite, anxiety, excitation, agitation, hostility, aggression, rage, blood dyscrasias, increased bilirubin and liver transaminases levels. This is not an exhaustive list of side effects, so it is important to consult a doctor for more information and seek immediate medical advice if any side effects occur.

What other drugs will affect Lorazepam?

Taking Lorazepam with certain medications can cause excessive drowsiness, slowed breathing, or other dangerous side effects. It is important to inform your doctor about all the medications you are taking, especially opioids, muscle relaxants, sleeping pills, or other medications for anxiety or seizures. Sodium oxybate and valerian are also known to interact with Lorazepam. It is advisable to consult a doctor for any concerns or questions regarding drug interactions.

What happens when you miss a dose or overdose?

If you miss a dose of Lorazepam, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and do not take two doses at once. Overdosing on Lorazepam can be serious, especially when combined with alcohol, opioids, or other medications that cause drowsiness or slow breathing. Symptoms of overdose may include confusion, slurred speech, restlessness, muscle weakness, loss of balance or coordination, weak or shallow breathing, or coma. In case of overdose, seek immediate medical attention.

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