Vyvanse and Drug Screenings
Vyvanse (lisdexamfetamine) has the potential to cause a positive test for amphetamine on a standard work or U.S. Department of Transportation urine drug screening. Most drug screening panels test urine for a range of different drugs, with the top five substances being amphetamines, cocaine, opiates, phencyclidine (PCP), and marijuana (THC). If you are having a drug screening, it will most likely include a test for amphetamines.
Vyvanse Drug Test Detection Time
Once you take Vyvanse, the average time it takes for the active drug to leave the body and be undetectable in a urine drug test is roughly 2.5 days (60 hours). However, this time can vary from person-to-person depending on factors such as age, weight, genetics, dose and frequency of use, other medications taken, and kidney function. The average time it stays in the body is determined by the drug’s half-life. In adults, the half-life is approximately 11 hours. Multiplying this by 5.5 gives an average time of 60 hours or 2.5 days for most of the drug to leave the body.
Prescribed Vyvanse and Drug Screenings
If you are prescribed Vyvanse for hyperactivity disorder (ADHD) or moderate to severe binge eating disorder, you should inform your employer in advance that you are taking this medication. If you have already had your drug screening and Vyvanse causes a positive test for amphetamine, you should be given the opportunity to provide proof of prescription or have a letter from your prescriber verifying that you are legitimately taking Vyvanse as a prescribed medication for your medical condition.
Bottom Line
Vyvanse can cause a positive test for amphetamines in drug screenings, and its average time to leave the body is 2.5 days but varies from person-to-person. If you test positive for amphetamines in a drug screening, you should provide proof to your employer that you are legitimately taking Vyvanse as a prescribed medication.